The Precursor To All Steroid Hormones! What is it and where does it come from? Pregnenolone (3-Hydroxypregn-5-en-20-one; delta 5-pregnen-3 beta-ol-20-one, and 17 beta-(1-ketoethyl)-delta 5-androstene-3 beta-ol) is a steroid hormone that is manufactured from cholesterol by cellular mitochondria. It is found in human nervous system tissues1, including the adrenal glands, the skin, the retina of the …

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